Helicobacter pylori as a causal agent of gastric pathologies diagnosed in patients at the Ecuatorian Institute of Digestive Diseases, Ecuador
Abstract
Helicobacter pylori is a gramnegative bacterium that inhabits the human gastric mucosa. It is one of the causative agents of gastric diseases as gastritis and gastric cancer. The purpose of this investigation was to determine the prevalence of H. pylori by the urease test, and its association with gastric pathologies, in patients aged 25-50 years that were treated at the Ecuadorian Institute of Digestive Diseases in Portoviejo, Ecuador, during the year 2018. Association between H. pylori infection and the manifestation of digestive pathologies, and the relationship between both age and gender, and H. pylori infection was evaluated by the Chi-square statistic. Odds ratios were calculated to establish whether the presence of H. pylori was a risk factor for the development of gastric or lower digestive system pathologies. From the patients diagnosed with pathologies of the digestive system, 31.11% were infected with H. pylori, and 24.3% possessed pathologies of the middle digestive tract. An association between bacterial infection and the occurrence of gastric disorders was clearly demonstrated. Moreover, it was established that H. pylori is a risk factor for the appearance of antral ulcer and erythematous pangastritis. The infection is not associated with age or gender of the patients
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