Artritis y alteraciones en la microbiota intestinal
Arthritis and gut microbiota dysbiosis
Palabras clave:
Microbiota, artritis, disbiosis
Resumen
El estudio de la microbiota desde el inicio de este siglo ha permitido conocer mejor sus características e interrelación con el huésped, y los mecanismos por los que esta favorece o perjudica su salud. Esto ha fortalecido de una manera más clara las hipótesis que datan del siglo XIX en donde se proponía a los microorganismos como causantes de enfermedad autoinmune. En esta revisión se expondrán algunos de los datos que apoyan la alteración de la microbiota, llamada disbiosis con el desarrollo y mayor severidad de artritis reumatoide (AR), y de cómo la renovación del equilibrio de la microbiota mediante estrategias terapéuticas ha demostrado ser favorable en el control de la enfermedad articular.
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Lederberg J, McCray A. Ome Sweet ’Omics - A Genealogical Treasury of Words. The Scientist. 2001; 15(7): 8-8.
Clemente J, Manasson J, Scher J. The role of the gut microbiome in systemic inflammatory disease. BMJ. 2018; 360:j5145.
Brüssow H. Problems with the concept of gut microbiota dysbiosis. Microbial biotechnology. 2020; 13(2):423-434.
Eckburg P, Bik E, Bernstein C, et al. Diversity of the human intestinal microbial flora. Science. 2005; 308(5728):1635–1638.
Zoetendal E, Akkermans A, Vos W. Temperature Gradient Gel Electrophoresis Analysis of 16S rRNA from Human Fecal Samples Reveals Stable and Host-Specific Communities of Active Bacteria. Appl Environ Microbiol. 1998; 64(10):3854–3859.
Aguiar V, Huang W, Suarez V, et al. Metatranscriptomics, and metabolomics approaches for microbiome analysis. Evol Bioinform Online. 2016; 12(1):5–16.
Wang Q, Xu R. Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis.2019; 20(1):124.
Honda K, Littman D. The microbiome in infectious disease and inflammation. Annu Rev Immunol. 2012; 30(1):759–95.
Manasson J, Blank R, Scher J. The microbiome in rheumatology: Where are we and where should we go?. Ann Rheum Dis. 2020; 79(6):727–733.
Mielants H, Veys E, De Vos M, Cuvelier C, Goemaere S, De Clercq L et al. The evolution of spondyloarthropathies in relation to gut histology. I. Clinical aspects. J. Rheumatol. 1995; 22(12):2266–2272.
Yatsunenko T, Rey F, Manary M, Yatsunenko T, Rey F, Manary M, et al. Human gut microbiome viewed across age and geography. Nature. 2012; 486(7402):2227.
Yang Q, Wang Y, Jia A, Wang Y, Bi Y, Liu G. The crosstalk between gut bacteria and host immunity in intestinal inflammation. 2021; 236(4):2239-2254.
Ivanov I, Atarashi K, Manel N et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 2009; 139(3):485-498.
Maeda Y, Takeda K. Host–microbiota interactions in rheumatoid arthritis. Experimental & Molecular Medicine. 2019; 51(12):1-6.
Corrêa J, Fernandes G, Calderaro D, Mendonça S, Silva J, Albiero M et al. Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients. Scientific reports. 2019; 9(1):8379.
du Teil M, Gabarrini G, Harmsen H, Westra J, van Winkelhoff1 A, Maarten J. Talk to your gut: the oral-gut microbiome axis and its immunomodulatory role in the etiology of rheumatoid arthritis. FEMS Microbiology Reviews. 2019; 43(1):1–18.
Lee Y, Lew P, Cheah C, Rahman M, Baharuddin N, Vaithilingam R. Potential mechanisms linking periodontitis to rheumatoid arthritis. J Int Acad Periodontol. 2019; 21(3):99-110.
Lucchino B, Spinelli F, Iannuccelli C, Guzzo M, Conti F, Franco M. Mucosa–environment interactions in the pathogenesis of rheumatoid arthritis. Cells. 2019; 8(7):700.
Gómez E, Mukherjee A, Darrah E, Andrade F. Rheumatoid arthritis-associated mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Journal of clinical medicine. 2019; 8(9):1309.
Alpizar D, Lesker T, Gronow A, Gilbert B, Raemy E, Lamacchia, C et al. Prevotella copri in individuals at risk for rheumatoid arthritis. Annals of the rheumatic diseases. 2019; 78(5):590-593.
Garabatos N., Santamaria, P. Gut microbial antigenic mimicry inautoimmunity. Front. Immunol. 2022; 13: 873607.
Chiang, H, Li J, Liu C, Liu P, Chen H, Chen Y et al. An association of gut microbiota with different phenotypes in Chinese patients with rheumatoid arthritis. J. Clin. Med. 2019; 8(11):1770.
Zaiss M, Taijc N, Sarter K, Azizov V, Bucci L, Luo Y et al. Mcrobiota-induced intestinal barrier dysfunction precedes the onset of arthritis and allows the shuttling of immune cells from the gut the joints. 2020; 79:154.
Li S, Bostick, J, Zhou L. Regulation of innate lymphoid cells by aryl hydrocarbon receptor. Front. Immunol. 2018; 8:1909.
Koppejan H, Jansen D, Hameetman M, Thomas R, Toes R, van Gaalen F. Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis research & therapy. 2019; 21(3):1-7.
Yang W, Yu T, Cong, Y. CD4(+) T cell metabolism, gut microbiota, and autoimmune diseases: implication in precision medicine of autoimmune diseases. Precis Clin. Med.2022; 5(3):pbac018.
He J, Chu Y, Li J, Meng Q, Liu, Y, Jin J, et al. Intestinal butyrate metabolizing species contribute to autoantibody production and bone erosion in rheumatoid arthritis. Sci. Adv. 2022; 8(6):eabm1511.
Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H et al. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells. EBioMedicine. 2020; 58:102913.
Xu H, Pan L, Yu H, Han P, Fu J, Zhang Z et al. Gut microbiotaderived metabolites in inflammatory diseases based on targeted metabolomics. Front. Pharmacol. 2022;13:919181.
Stone M., Fortin P., Pacheco C, Inman R. Should tetracycline treatment be used more extensively for rheumatoid arthritis? Metaanalysis demonstrates clinical benefit with reduction in disease activity. J. Rheumatol. 2003; 30(10): 2112–2122.
Aqaeinezhad R, Rahmdel S, Abdollahzadeh S, Zare M, Bazrafshan A, Mazloomi S. The efficacy of probiotic supplementation in rheumatoid arthritis: a meta-analysis of randomized, controlled trials. Inflammopharmacology. 2018; 26:67–76.
Häger J, Bang H, Hagen M, French M, Trager P, Sokolova M, et al. The role of dietary fiber in rheumatoid arthritis patients: a feasibility study. Nutrients. 2019; 11(10):2392.
Alrafas H, Busbee P, Nagarkatti M, Nagarkatti P. Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells. J. Leukoc. Biol. 2019; 106(2):467–480.
Maier L, Pruteanu M, Kuhn M, Zeller G, Telzerow A, Anderson A et al. Extensive impact of non- antibiotic drugson human gut bacteria. Nature. 2018; 555(7628):623–628.
Bodkhe R, Balakrishnan B, Taneja V. The role of microbiome in rheumatoid arthritis treatment. Therapeutic Advances in Musculoskeletal Disease. 2019; 11:1-16.
De Luca F, Shoenfeld Y. The microbiome in autoimmune diseases. Clinical and Experimental Immunology. 2019; 195:74–85.
Clemente J, Manasson J, Scher J. The role of the gut microbiome in systemic inflammatory disease. BMJ. 2018; 360:j5145.
Brüssow H. Problems with the concept of gut microbiota dysbiosis. Microbial biotechnology. 2020; 13(2):423-434.
Eckburg P, Bik E, Bernstein C, et al. Diversity of the human intestinal microbial flora. Science. 2005; 308(5728):1635–1638.
Zoetendal E, Akkermans A, Vos W. Temperature Gradient Gel Electrophoresis Analysis of 16S rRNA from Human Fecal Samples Reveals Stable and Host-Specific Communities of Active Bacteria. Appl Environ Microbiol. 1998; 64(10):3854–3859.
Aguiar V, Huang W, Suarez V, et al. Metatranscriptomics, and metabolomics approaches for microbiome analysis. Evol Bioinform Online. 2016; 12(1):5–16.
Wang Q, Xu R. Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis.2019; 20(1):124.
Honda K, Littman D. The microbiome in infectious disease and inflammation. Annu Rev Immunol. 2012; 30(1):759–95.
Manasson J, Blank R, Scher J. The microbiome in rheumatology: Where are we and where should we go?. Ann Rheum Dis. 2020; 79(6):727–733.
Mielants H, Veys E, De Vos M, Cuvelier C, Goemaere S, De Clercq L et al. The evolution of spondyloarthropathies in relation to gut histology. I. Clinical aspects. J. Rheumatol. 1995; 22(12):2266–2272.
Yatsunenko T, Rey F, Manary M, Yatsunenko T, Rey F, Manary M, et al. Human gut microbiome viewed across age and geography. Nature. 2012; 486(7402):2227.
Yang Q, Wang Y, Jia A, Wang Y, Bi Y, Liu G. The crosstalk between gut bacteria and host immunity in intestinal inflammation. 2021; 236(4):2239-2254.
Ivanov I, Atarashi K, Manel N et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 2009; 139(3):485-498.
Maeda Y, Takeda K. Host–microbiota interactions in rheumatoid arthritis. Experimental & Molecular Medicine. 2019; 51(12):1-6.
Corrêa J, Fernandes G, Calderaro D, Mendonça S, Silva J, Albiero M et al. Oral microbial dysbiosis linked to worsened periodontal condition in rheumatoid arthritis patients. Scientific reports. 2019; 9(1):8379.
du Teil M, Gabarrini G, Harmsen H, Westra J, van Winkelhoff1 A, Maarten J. Talk to your gut: the oral-gut microbiome axis and its immunomodulatory role in the etiology of rheumatoid arthritis. FEMS Microbiology Reviews. 2019; 43(1):1–18.
Lee Y, Lew P, Cheah C, Rahman M, Baharuddin N, Vaithilingam R. Potential mechanisms linking periodontitis to rheumatoid arthritis. J Int Acad Periodontol. 2019; 21(3):99-110.
Lucchino B, Spinelli F, Iannuccelli C, Guzzo M, Conti F, Franco M. Mucosa–environment interactions in the pathogenesis of rheumatoid arthritis. Cells. 2019; 8(7):700.
Gómez E, Mukherjee A, Darrah E, Andrade F. Rheumatoid arthritis-associated mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Journal of clinical medicine. 2019; 8(9):1309.
Alpizar D, Lesker T, Gronow A, Gilbert B, Raemy E, Lamacchia, C et al. Prevotella copri in individuals at risk for rheumatoid arthritis. Annals of the rheumatic diseases. 2019; 78(5):590-593.
Garabatos N., Santamaria, P. Gut microbial antigenic mimicry inautoimmunity. Front. Immunol. 2022; 13: 873607.
Chiang, H, Li J, Liu C, Liu P, Chen H, Chen Y et al. An association of gut microbiota with different phenotypes in Chinese patients with rheumatoid arthritis. J. Clin. Med. 2019; 8(11):1770.
Zaiss M, Taijc N, Sarter K, Azizov V, Bucci L, Luo Y et al. Mcrobiota-induced intestinal barrier dysfunction precedes the onset of arthritis and allows the shuttling of immune cells from the gut the joints. 2020; 79:154.
Li S, Bostick, J, Zhou L. Regulation of innate lymphoid cells by aryl hydrocarbon receptor. Front. Immunol. 2018; 8:1909.
Koppejan H, Jansen D, Hameetman M, Thomas R, Toes R, van Gaalen F. Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis research & therapy. 2019; 21(3):1-7.
Yang W, Yu T, Cong, Y. CD4(+) T cell metabolism, gut microbiota, and autoimmune diseases: implication in precision medicine of autoimmune diseases. Precis Clin. Med.2022; 5(3):pbac018.
He J, Chu Y, Li J, Meng Q, Liu, Y, Jin J, et al. Intestinal butyrate metabolizing species contribute to autoantibody production and bone erosion in rheumatoid arthritis. Sci. Adv. 2022; 8(6):eabm1511.
Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H et al. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells. EBioMedicine. 2020; 58:102913.
Xu H, Pan L, Yu H, Han P, Fu J, Zhang Z et al. Gut microbiotaderived metabolites in inflammatory diseases based on targeted metabolomics. Front. Pharmacol. 2022;13:919181.
Stone M., Fortin P., Pacheco C, Inman R. Should tetracycline treatment be used more extensively for rheumatoid arthritis? Metaanalysis demonstrates clinical benefit with reduction in disease activity. J. Rheumatol. 2003; 30(10): 2112–2122.
Aqaeinezhad R, Rahmdel S, Abdollahzadeh S, Zare M, Bazrafshan A, Mazloomi S. The efficacy of probiotic supplementation in rheumatoid arthritis: a meta-analysis of randomized, controlled trials. Inflammopharmacology. 2018; 26:67–76.
Häger J, Bang H, Hagen M, French M, Trager P, Sokolova M, et al. The role of dietary fiber in rheumatoid arthritis patients: a feasibility study. Nutrients. 2019; 11(10):2392.
Alrafas H, Busbee P, Nagarkatti M, Nagarkatti P. Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells. J. Leukoc. Biol. 2019; 106(2):467–480.
Maier L, Pruteanu M, Kuhn M, Zeller G, Telzerow A, Anderson A et al. Extensive impact of non- antibiotic drugson human gut bacteria. Nature. 2018; 555(7628):623–628.
Bodkhe R, Balakrishnan B, Taneja V. The role of microbiome in rheumatoid arthritis treatment. Therapeutic Advances in Musculoskeletal Disease. 2019; 11:1-16.
De Luca F, Shoenfeld Y. The microbiome in autoimmune diseases. Clinical and Experimental Immunology. 2019; 195:74–85.
Publicado
2024-05-23
Cómo citar
Materano Blanco , R. (2024). Artritis y alteraciones en la microbiota intestinal: Arthritis and gut microbiota dysbiosis. Revista Profesional HígadoSano, (27), 29-35. https://doi.org/10.5281/zenodo.11265429
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