TORCH and human Parvovirus B19 infections in pregnant women: therapeutic and diagnostic implications. Systematic Review

  • Nereida Josefina Valero Cedeño South Manabi State University. Faculty of Health Sciences. Clinical Laboratory Career. http://orcid.org/0000-0003-3496-8848
  • José Daniel López-Guillen Universidad Estatal del Sur de Manabí. Facultad de Ciencias de la Salud. Carrera de Laboratorio Clínico. Jipijapa-Manabí. Ecuador
  • Esteban Leonardo Guadamud-Zamora Universidad Estatal del Sur de Manabí. Facultad de Ciencias de la Salud. Carrera de Laboratorio Clínico. Jipijapa-Manabí. Ecuador
  • Teresa Isabel Veliz-Castro Universidad Estatal del Sur de Manabí. Facultad de Ciencias de la Salud. Carrera de Laboratorio Clínico. Jipijapa-Manabí. Ecuador
DOI: https://doi.org/10.5281/zenodo.5577846
Keywords: toxoplasmosis, syphilis, cytomegalovirus, herpes simplex, HIV, Human Parvovirus B19, serological tests, polymerase chain reaction, immunization, therapy

Abstract

Congenital infections are one of the main causes of fetal-neonatal morbidity and mortality. The aim of the study was to analyze human TORCH and Parvovirus B19 infections in pregnant women and their therapeutic and diagnostic implications. A documentary design was used by means of a bibliographic search in scientific databases such as: PubMed. Elsevier, Scielo, Redalyc, Google Scholar, Microsoft Academic, Dialnet, and DOAJ, using as keywords: Toxoplasmosis, cytomegalovirus, rubella, syphilis, herpes simplex, HIV, human Parvovirus B19. Articles in English and Spanish published from 2015 onwards, selected under inclusion and exclusion criteria, were included. Congenital infections remain common in developing countries, with significant complications and even death; hence the importance of monitoring and diagnosing pregnant women. It is evident that these infections are a public health problem, the most frequent being caused by cytomegalovirus. Serological and molecular tests of high sensitivity and specificity are used for an accurate diagnosis. In the epidemiological and therapeutic implications, prevention for rubella, therapeutic approach and cesarean section are evidenced, in order to reduce perinatal consequences such as central nervous system involvement and congenital malformations that represent a high risk of abortion and fetal death

Author Biography

Nereida Josefina Valero Cedeño, South Manabi State University. Faculty of Health Sciences. Clinical Laboratory Career.

Degree in Bioanalysis. Magister Scientiarum in Biology, Mention Basic Immunology. Doctor in Immunology. Postdoctorate in Immunology and Infectious Diseases. Teacher-Researcher hired. Clinical Laboratory Career. Faculty of Health Sciences. Southern State University of Manabi. Manabí-Ecuador, among the different positions held, are former Director of the Institute of Clinical Research “Dr. Américo Negrette. ” Faculty of Medicine, University of Zulia. Maracaibo Venezuela. Former head of the Virology Section. Institute of Clinical Research. "Dr. Américo Negrette. ” Faculty of Medicine, University of Zulia. Maracaibo Venezuela. Former director of the Research Division of the Faculty of Medicine, Universidad del Zulia. Maracaibo Venezuela. Ex-coordinator of the Research Master in Biomedicine. Institute of Clinical Research. "Dr. Américo Negrette. ” Faculty of Medicine, University of Zulia. Maracaibo Venezuela. Ex-coordinator of the Master in Infectious Diseases of the University of Alcalá, Spain. Professional experience in the areas of immunology and virology. His research focuses on the diagnosis and epidemiology of emerging and reemerging viral infections such as Venezuelan equine encephalitis, dengue fever, yellow fever and respiratory syncytial virus among others. He has presented numerous communications to congresses and lectured at national and international scientific events. He has published more than 110 scientific papers in refereed journals, as well as reviews, chapters in books and monographs, both nationally and internationally. Member of the Editing Commission and expert evaluator in the area of immunology and virology of the Clinical Research Journals, Kasmera, REDIELUZ, Medical Journal of the Dr. Adolfo Pons Hospital and of the Ibero-American Journal of Applied Research. Member of the Venezuelan Society of Microbiology, Member of the American Society of Tropical Medicine and Hygiene (ASTMH) and Member of the Venezuelan Association for the Advancement of Science (AsoVAC).

E-mail: nere98@hotmail.com  valero.nereida@gmail.com

ORCID ID: https://orcid.org/0000-0003-3496-8848

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Published
2021-10-18
How to Cite
1.
Valero Cedeño NJ, López-Guillen JD, Guadamud-Zamora EL, Veliz-Castro TI. TORCH and human Parvovirus B19 infections in pregnant women: therapeutic and diagnostic implications. Systematic Review. Kasmera [Internet]. 2021Oct.18 [cited 2025Apr.4];49(Supl 1):e49S136130. Available from: https://mail.produccioncientificaluz.org/index.php/kasmera/article/view/36130
Issue
Vol. 49 No. Supl 1 (2021)
Section
Sistematic Review and/or Metaanaliysis

Copyright (c) 2021 Nereida Josefina Valero Cedeño, José Daniel López-Guillen, Esteban Leonardo Guadamud-Zamora, Teresa Isabel Veliz-Castro

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