Prevalence and sociodemographic characteristics of ADHD-cannabis comorbidity in outpatients of the Maracaibo Psychiatric Hospital
Abstract
Attention-Deficit/Hyperactivity Disorder (ADHD) and Cannabis Use Disorder (CUD) exhibit substantial comorbidity, linked to neurobiological and environmental factors, with increased risk of early substance use and functional impairment. This cross-sectional descriptive study aimed to determine the prevalence and sociodemographic characteristics of this comorbidity in 35 outpatients from the Psychiatric Hospital of Maracaibo (consecutive sampling, January-March 2025), applying DSM-5
criteria and statistical analysis with SPSS. Results showed a male predominance (68.6%), age 18-28
years (65.7%), high employment rates (82.9%), and secondary education (57.1%). The hyperactive-im-
pulsive subtype had the highest current CUD prevalence (77%), while the inattentive subtype showed the highest lifetime prevalence (38%). Cannabis use began earlier in ADHD patients (12-18 years) compared to other diagnoses (15-25 years), with fewer additional psychiatric comorbidities (25% vs. 65%). Findings suggest impulsivity is linked to immediate risk and inattention to chronic vulnerability, highlighting the need for early prevention, integrated dual-diagnosis treatment, and psychosocial support to mitigate functional impact.
Downloads
References
DSM-5 y estudios neurobiológicos y epidemioló-
gicos sobre TDAH y TCc: American Psychiatric
Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing. https://doi.org/10.1176/appi.books.9780890425596
European Psychiatry Association. (2023). Cannabis use in ADHD: Neurocognitive and treatment considerations. European Child & Adolescent Psychiatry, 32, 1-15. https://doi.org/10.1007/s00787-023-02169-w
Foster, K. T., Arterberry, B. J., Zucker, R. A., & Hicks, B. M. (2018). Psychosocial functioning among regular cannabis users with and without cannabis use disorder. Psychological Medicine, 48(11), 1853-1861. https://doi.org/10.1017/S0033291717003361
Froude A M., Fawcett E J., Coles A, Drakes D H., Ha-
rris N, Fawcett J M. (2024), The prevalence of can-
nabis use disorder in attention-deficit hyperactivity
disorder: A clinical epidemiological meta-analysis, Journal of Psychiatric Research, Volume 172, 2024, Pages 391-401, ISSN 0022-3956, https://pubmed.ncbi.nlm.nih.gov/38452637/, https://doi.org/10.1016/j.jpsychires.2024.02.050.
Lee, S., & Hong, S.-B. (2022). Thalamocortical functional connectivity and cannabis use in men with childhood attention-deficit/hyperactivity disorder. PLOS ONE, 17(11), e0278162. https://doi.org/10.1371/journal.pone.0278162
Liebregts, N., van der Pol, P., Van Laar, M., de Graaf, R., van den Brink, W., & Korf, D. J. (2013). The role of study and work in cannabis use and dependence trajectories among young adults. Frontiers in Psychiatry, 4, 85. https://doi.org/10.3389/fpsyt.2013.00085
Loflin, M., Earleywine, M., De Leo, J., & Hobkirk, A. (2014). Subtypes of attention-deficit/hyperactivity disorder (ADHD) and cannabis use. Substance 73 Use & Misuse, 49(4), 427-434. https://doi.org/10.3109/10826084.2013.841251
McCabe, S. E., Veliz, P., & Schulenberg, J. (2023). Translating the nuanced risk for substance use among adolescents prescribed ADHD medication. Journal of Child Psychology and Psychiatry, 64(2),221-224. https://doi.org/10.1111/jcpp.13888
Petker, T., Ferro, M., Van Ameringen, M., Murphy, J., & MacKillop, J. (2021). Daily, but not occasional, cannabis use is selectively associated with impulsive delay discounting and hyperactive ADHD symptoms in binge-drinking young adults. Psychopharmacology, 238(7), 1753-1763. https://doi.org/10.1007/s00213-021-05781-3
Sibley, M. H., Pelham, W. E., Molina, B. S. G., Coxe, S., Kipp, H., Gnagy, E. M., ... Lahey, B. B. (2022). Early substance use in the pathway from childhood ADHD to young adult substance disorders.
Addictive Behaviors, 134, 107420. https://doi.org/10.1016/j.addbeh.2022.107420
Copyright (c) 2025 Douglas E Parra L

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright
Authors who publish in this journal agree to the following terms:
Authors retain copyright and grant the journal the right to be the first publication where the article is submitted, which is published under a Creative Commons Attribution License, which allows others to share the work upon acknowledgment of authorship of the work and initial publication in this journal.
Authors may separately enter into additional agreements for non-exclusive distribution of the version of the work published in the journal (e.g., placing it in an institutional repository or publishing it in a book), with an acknowledgement of its initial publication in this journal.
This work is licensed under the license:
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).